Frequency of Apolipoprotein E Alleles in Iranian Populations
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Association of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in Iranian Patients
Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...
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گسترش سریع تکنولوژی و اینترنت مسیر شرکت ها را به نگهداری وفاداری مشتریان الکترونیکی معطوف کرده است. وفاداری مشتریان یک حوزه بسیار جالب برای شرکت ها می باشد و وفاداری مشتریان تاثیر مستقیم بر درآمد و سودزایی شرکتها دارد. با توجه به اهمیت وفاداری مشتری، ما به جستجوی سه مشکل اصلی تحقیق پرداختیم که آن ها مهمترین موانع برای حفظ حیات کسب و کارهای اینترنتی هستند که عبارت از تعویض های متعدد مشتری، هزینه...
15 صفحه اولassociation of apolipoprotein e alleles with susceptibility to age-related macular degeneration in iranian patients
background: we aimed here to investigate the association between alleles and genotypes of apoe and age-related macular degeneration (amd) development. materials and methods: after ophthalmological examination, 120 patients with confirmed amd and 120 healthy controls were enrolled in the study. the polymorphic segment of apoe gene was pcr-amplified and sequenced to determine the frequency distri...
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Apolipoprotein E (apo E) is a structural constituent of several serum lipoprotein classes. It plays an important role in lipid metabolism by acting as a ligand for low-density lipoprotein (LDL) and chylomicron remnant receptors. Three common alleles called e2, e3 and e4 have been described, which code for three protein isoforms (E2, E3 and E4). The polymorphism is clinically significant, and it...
full textThe distribution of apolipoprotein E alleles in Scottish perinatal deaths.
BACKGROUND The apolipoprotein E (ApoE) polymorphism has been well studied in the adult human population, in part because the e4 allele is a known risk factor for Alzheimer's disease. Little is known of the distribution of ApoE alleles in newborns, and their association with perinatal brain damage has not been investigated. METHODS ApoE genotyping was undertaken in a Scottish cohort of perinat...
full textDistribution of apolipoprotein E alleles in the Omani population.
OBJECTIVE To estimate the apolipoprotein E (apo E) allele distribution in the Omani population and to compare them with those of other populations. SUBJECTS AND METHODS One hundred and sixty-two healthy Omanis of Arab Bedouin origin were genotyped by polymerase chain reaction followed by restriction fragment length polymorphism. RESULTS The apo E allele frequencies were: epsilon2, 0.052; ep...
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Journal title
volume 4 issue 2
pages 141- 141
publication date 2006-04-01
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